Wednesday, December 25, 2019

Assingment 2.1 - 816 Words

Assignment 2.1 E5-1 Assumed a firm makes a $2,500 deposit into its money market account. If this account is currently paying 0.7% (yes, that’s right, less than 1%!), what will the account balance be after 1 year? The answer is $2,517.5 E5-2 If Bob and Judy combine their savings of $1,260 and $975, respectively, and deposit this amount into an account that pays 2% annual interest, compounded monthly, what will the account balance be after 4 years? The answer is $2,419.2358 E5-3 Gabrielle just won $2.5 million in the state lottery. She is giving the option of receiving a total of $1.3 million now, or she can elect to be paid $100,000 at the end of each of the next 25 years. If Gabrielle can earn 5% annually on her†¦show more content†¦He has plenty of money but little financial sense. He received a gift of $12,000 for his recent graduation and is looking for a bank in which to deposit these funds. Partners Savings Banks offers an account with an annual interest rate of 3% compounded semiannually, while Selwyns offers an account with a 2.75% annual interest rate compounded continiously. Calculate the value of the two accounts at the end of one year, and recommend to Joseph which account he should choose. In the first option investing the $12,000 with an annual interst rate compounded semiannually will have at the end of the year $12,730.80. In the second option investing the $12,000 with a 2.75% annual interest rate compounded continiously he will have at the end of the year $12,365.45. I believe is in the best interest for Joseph to go with the first option that will result at the end of the year in $12,730.80. E5-6 Jack and Jill have just had their first child. If college is expected to cost $150,000 per year in 18 years, how much should the couple begin depositing annually at the end of each year to accumulate enough funds to pay the first years tuition at the beginning of the 19th year? Assume that they can earn a 6% annual rate of return on their investment. Jack and Jill have to deposit annually at the end of each year $4,853.00 to achieve their goal of $150,000 in 18 years. In this journey of personal discovery in the finance world I came across a variety of veryShow MoreRelatedAssingments 2012-20134348 Words   |  18 PagesASSINGMENTS 2012-2013 Marketing Studies (1 year, Diploma) 1 BUSINESS ENGLISH Assignment 1 a) Luis St. Jean is a famous design house in France with annual sales of $1.2 billion in clothing, perfume, scarves, and other designer items. Each year it prepares more than 150 original designs for its seasonal collections. As head buyer for Cindy’s, an upscale women’s clothing store at the Mall of America in Minneapolis, you think you might like to start offering the LSJ’s line of perfume

Tuesday, December 17, 2019

The Prolonged Effects of Steroids Essay - 791 Words

Think of a world where the only thing an athlete has to do to become the next Michael Jordan, Babe Ruth, or Jesse Owens is take a pill or take a harmless injection. The injections and pills are harmless for now. When abused the effects of anabolic steroids are lethal. Anabolic steroids are an illegal drug unlike their counterpart, the corticosteroids. You will soon learn the consequences of using an illegal advantage of steroids in sports and on the body. If you want to know about the effects of steroids you first must know what steroids are. Steroids are a medicine taken by mouth or injection and, when used correctly can heal your injury and overall health. Corticosteroids were invented by scientists at the Mayo Clinic in†¦show more content†¦If an adolescent takes anabolic steroids, it will stunt his or her growth. Anabolic steroids are helpful in maintaining muscle in people with AIDS and are sometimes prescribed for men with hormone problems (C, Alicia). Roid Rage is a m ajor side effect of steroids because it causes random fits of aggression (Anabolic Steroids). WWE star, Chris Benoit, killed himself and his family after what was believed to be a fit of severe road rage. Steroids are a growing problem in professional sports. Athletes use steroids to build lean muscle mass, promote aggressiveness, and increase body weight. Some athletes take two or more anabolic steroids together, mixing oral and injectable types (Anabolic Sports). Major League Baseball has the most cases of steroid, or PED (performance enhancing drugs), suspensions. There have been dozens of suspensions over the years by the MLB by taking daily drug tests. A program has been developed for both male and female sports teams (ATLAS for guys and ATHENA for girls) to teach the dangers of drugs and steroids. Teenage girls use steroids to improve or change their body types. In 2005, 4% of high school students tried steroids; in 2012, only 1.8% of teens experimented with steroids (11 Facts ). Some baseball fans do not like the fact that the MLB banned PEDs because it takes the excitement away from the game. My opinion of PEDs is watching men who abide by the rules of the game play baseball the way it was meant to be played. I don’tShow MoreRelatedAnabolic Androgenic Steroids Is A Huge Problem Among Today s Athletes857 Words   |  4 Pages Vidden 14 January 2015 Anabolic-Androgenic Steroid Abuse in Professional Sports Anabolic-androgenic steroids are a huge problem amongst today’s athletes. The use of these drugs has been around for many years in sports. Understanding anabolic-androgenic steroids and why people take them is needed in the process of trying to eliminate them from professional sports. Also, players knowing and understanding how the negatives of anabolic-androgenic steroid use outweigh the positives will hopefully helpRead MoreEssay about Steroid Use in People Everywhere 745 Words   |  3 PagesAnabolic steroids can weaken the body’s defenses against viral infections and cancers, even at doses much smaller than those used by cheating athletes. If they are weakened, viral diseases and tumors may find it easier to take hold in the body, potentially placing those who take steroids for prolonged periods at risk. Athletes have used these drugs for a long time, â€Å"Dr. Weatherby said, But now for the first time we were able to show that androgenic anabolic steroids have a seriously detrimental effectRead MoreThe Negative Effects of Steroid Use754 Words   |  3 PagesSteroids can affect an athlete’s physical health. Developing breasts from steroid use is very common. Breasts develop because when high doses of steroids are used for prolonged periods, they shut down certain hormones such as testosterone. Studies show that estrogen is what causes breast tissue growth; progesterone needs to be available in order to keep breast size down. Shrunken testicles can also occur because when a person uses steroids, they introduce a new hormone from outside their body atRead MoreSteroids And Athletes Should Not Be Allowed1234 Words   |  5 PagesSteroids and Athletes What is the best way to get big quick? Most would say to go to the gym or start a more intense workout program and eat right. It is contrary for some professional athletes that go against the correct way to maximize their strength and take steroids. Most your sport competitors participate in sports to have the opportunity to put their abilities against those of their peers. Many athletes are determined to win at all cost. They may use that determination to justify the use ofRead MoreAnabolic Steroids Should Be Banned Essay1814 Words   |  8 PagesFor years, anabolic steroids have been used by competitive athletes have used to improve performance through muscular size or strength, and by noncompetitive weight trainers for purely cosmetic physique enhancement. In the vast majority of cases, users of that have taken steroids for prolonged periods have reported considerable gains in physical size and strength. However, a large number of side effects and health risks have been linked t o extended use of anabolic steroids. Research has indicatedRead MoreSteroids : Sports And Steroids1169 Words   |  5 PagesPresident George W. Bush says â€Å"Steroids are dangerous in sports and steroids send the wrong message: There are shortcuts to accomplishments and performance is more important than character.† Steroids are a hormone like substance made by the body. Steroids are closely related to the male prime hormone, testosterone which is the main development of male characteristics such as facial hair, deeper voice and larger muscles. It is bad to use steroids because they cause heart problems, hormonal issuesRead More The Use of Performance Enhancing Drugs in Sports Essay1148 Words   |  5 Pagesof the development of anabolic steroids: a group of powerful synthetic chemical compounds that resemble the natural male sex hormones (Schwarzenneger 722). Anabolic steroids were first developed in the 1930s as a therapeutic drug to treat growth hormone replacement in deficient children, menopausal symptoms, impotence, and the retardation of the effects of aging by stimulating the rate of synthesis of protein molecules (Biology 121 Web Project 1). These steroids are a simulated testosteroneRead MoreCase Study : Mr. Big Of New Zealand 1624 Words   |  7 Pagesnumbered and is trying (in spite of his slurred speech and hard-to-follow thought processes) to spread a message before he dies. That message is: DO NOT ABUSE ENHANCMENT DRUGS AND STEROIDS. Justin’s primary method of achieving his size was to experiment with whatever enhancement drug he could get his hands on including steroids. He basically turned his body into his own scientific guinea pig experimenting with enhancement drugs of all kinds to find the quickest way to gain size and strength. JustinRead MoreDrugs And Drugs In Sports1150 Words   |  5 Pagesfirst probl em with drugs are the side effects, especially from steroids. â€Å"Anabolic steroids use may cause the following: acne, decreased sperm count, decreased appetite, fatigue, impotence, mood swings, and insomnia†(Russell, 2017, para. 23). Prolonged use of steroids may affect mood and behavior of an individual. This can lead to any of the following effects: kidney failure, violence, blood diseases, heart attack, seizure, and even cancer (Russell, 2017). Steroids are a big no in any sport around theRead MoreLong Term Dangers Of Steroid Abuse2099 Words   |  9 Pages2015 Long Term Dangers of Steroid Abuse Anabolic Steroids are commonly viewed as a miracle drug in order to increase muscle growth and definition, but what most users of the drug don’t know are the life altering effects that prolonged use can cause. When the drug was released in the late 50’s by scientists working for the Soviet Union, they had no idea what the lasting effects were going to be. At first the drug seemed to be almost a miracle, it helped

Monday, December 9, 2019

Artemisinin An AntiMalaria Essay Research Paper INTRODUCTIONThe free essay sample

Artemisinin An Anti-Malaria Essay, Research Paper Introduction The figure people affected by malaria is increasing tremendously. This increasing is due to the fresh drug immune discrepancies of the parasite that causes malaria the Plasmodium. This opposition is a effect of the monolithic usage of the quinoline-related drugs over the last decennaries. In this scenario, it became of import to seek for new drugs, active against fresh biochemical parasite marks. The drug known as artemisin or Qinghaosu ( 1 ) , is a consequence of Chinese authorities run, to seek for new active drugs against malaria, in Chinese medicative workss. In the general mechanism accepted for the action of artemisin, the free heme group, obtained during the haemoglobin digestion is proposed to catalyze the formation of oxyl groups, by oxidization of the Fe ( II ) to Fe ( III ) and the decrease of the endoperoxide bond. These oxyl groups rearrange in to C-centred groups that are cytotoxic to the parasite by alkylation of critical parasite proteins. In the experiments directed in Liverpool, the first measure was to seek to synthesize fresh artemisin derived functions and so to make a biomimetic survey, with these compounds and the Fe salt FeCl. In the first experiment carried, it was tried to synthesize an quintessence ( 2 ) of the dihydroartemisin ( 3 ) and tetrazol chloride ( 4 ) , utilizing a method developed by University of Algarve Organic Chemistry group ( see scheme 1 ) Scheme 1 In the undermentioned experiments, and utilizing a different methodological analysis, it was tried to synthesize, with artemisin benzoate ( 5 ) and p-trifluoromethoxi phenol ( 6 ) as get downing stuff, the trifluoromethoxi phenol substituted compound ( 7 ) ( see scheme 2 ) Scheme 2 At last, it was done a biomimetic survey, responding the obtained compound with the Fe salt FeCl ( scheme 3 ) , arising two different merchandises: the one resulting from the formation of a primary C centred extremist ( 8 ) ; and from the formation of a secondary C-centered group ( 9 ) . Scheme 3 EXPERIMENTAL SECTION AND RESULTS Experiment I: Synthesis of Compound 2 The tetrazole chloride ( 0,12 g, 0,67 mmol ) was added to a solution of dihydroartemisin and NaH ( 0,053 mmol ) in dried tetrahydrofuran. The solution was stirred for 1 hr. The T.L.C. show that after this clip, there wasn T any merchandise on the reaction pot and the reaction should remain longer stirring Experiment II: Synthesis of Compound 7 A solution of benzoate ( 0.409, 1mmol ) in anhydrous dychlorometane ( 5 milliliter ) was added to a mixture of p-trifluoromethyl phenol ( 0.811, 5 mmol ) and ZnCl2 ( 0.1759, 1.25 mmol ) in anhydrous dychloromethane ( 4 milliliter ) , at 0| C.. The reaction was stirred for 1 hr and 15 proceedingss and followed by T.L.C. utilizing as eluent a solution of 75 % hexane, 25 % ethyl ethanoate. The reaction was so, diluted with ethyl ethanoate and washed 3 Ti Maines with a solution of 5 % of citric acid, saturated aqueous solution of Sodium hydrogencarbonate and dried with Mg sulfate. The dissolver was evaporated to dryness and the coveted merchandise was isolated utilizing a silicon oxide gel flash chromatography column ( with the same eluent used on the T.L.C. ) , recristalized, and was done an N.M.R. spectrometry. The output of this reaction was 19,7 % . Experiment III: Synthesis of Compound 7 The former process was repeated as antecedently described but in this experiment, the reaction was stirred at 0|C. for 2 hours, and left stirring during the dark at room temperature. The eluent used in the T.L.C. and in the silicon oxide flash chromatography column was besides changed. It was used a solution of 85 % of methylbenzene, 15 % of dychloromethane. In this instance there wasn T a great improve in the output ( 33.3 % ) , so the following measure will be to utilize a greater sum of the Lewis acid. Experiment IV: Synthesis of Compound 7 The former process was repeated as antecedently described but in this experiment, it was used 5mmol of the Lewis acid ( ZnCl2 ) and the reaction was stopped after two hours. The eluent used in the T.L.C. and in the silicon oxide flash chromatography column was besides changed. It was used a solution of 75 % of dychloromethane and 25 % of hexane. In the present experiment, the output was 67,7 % . Experiment V: Isomerization of the compound 7 The FeCl ( 68 milligram, 0,33 mmol ) was added to a solution of the compound III ( 150 milligram, 0,34 mmol ) in acetonitrile and was stirred for 45 proceedingss. The reaction was followed by T.L.C. utilizing 60 % methylbenzene, 40 % dychloromethane as eluent. The solution was filtered with celite, washed with dychloromethane and ethyl ethanoate and evaporated until waterlessness. The oil collected was purified utilizing a silicon oxide gel flash chromatography column with the same eluent. Merely a little sum of merchandise was isolated since it seemed like the merchandises interact with the silicon oxide gel. Experiment Six: The former experiment was repeated, but to insulate the merchandise, since it was suspected that the resulting merchandises somehow interact with the silicon oxide gel a impersonal aluminum oxide column was used with a solution of 80 % crude oil quintessence, 20 % ethyl ethanoate as eluent. At list one of the merchandises was isolated but the output was non determined. Recognitions I wish to thank to: Professora Lurdes and Professor Amadeu, non merely for the part that made this great chance happen, but besides for all forbearance, aid and knowledge given me during the last twelvemonth. Dr. Storr and Dr. Paul O Neill whose kindness, understanding, comprehension and support, made this dream possible. Rui, Ricardo, Steve, Vick, Tatiana and Ollie for all the aid and friendly relationship. I besides would wish to thank to the University of Liverpool for leting me to utilize all the installations.

Sunday, December 1, 2019

Love In Great Expectations Essay Research Paper free essay sample

Love In Great Expectations Essay, Research Paper Webster? s dictionary defines love in many different ways, ? A feeling of intense desire and attractive force toward a individual with whom one is disposed to do a brace ; the emotion of sex and love affair. To hold a feeling of intense desire and attractive force toward ( a individual ) ( Webster, love ) ? . In Great Expectations, Pip is traveling through adulthood, and is ever undergoing adulthood. We find that Pip is ever hankering for friends, household, and for love. Love can be a figure of things to different people. Love is an emotion, where there is no incorrect definition, for it suits each and every individual otherwise, nevertheless some features are the same amongst everybody. Pip thinks he is in love, but in my paper I investigate if it? s a existent desire of infatuation for Estella, or merely a first large crush which lasted through out his teenage old ages. We will write a custom essay sample on Love In Great Expectations Essay Research Paper or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Pip? s love for Estella is normally a one-way street, at least in his eyes. From the minute Pip meets her, he feels an attractive force towards her. At the same item, Estella? s outward feelings towards Pip are confounding and cruel. From slapping him in the face every bit hard as she can, to doing him experience every bit low as soil stating he has coarse custodies and thick colloidal suspensions and such, Estella is able to oppress Pip indoors. He feels as though he can non allow Estella cognize how he truly feels besides stating Miss Havisham and Estella her ego that she was reasonably, yet average. As clip goes on, Pip learns all about Estella from her attitude and visual aspect. This attitude and visual aspect is what Pip wanted to achieve so that Estella would love him. In chapter 17 Pip Tells Biddy? I am non at wholly happy as I am? ( Dickens, 127 ) . He wants to go a gentleman, a complement to a dame # 8211 ; Estella. Again stating his feelings to Biddy, he professes. ? the beautiful immature lady at Miss Havisham? s. And she? s more beautiful than anybody of all time was, and I admire her awfully, and I want to be a soft adult male on her history? ( Dickens, 129 ) . This is the first clip we learned about Pip? s love from Pip. Therefore far we assume that he likes her, but we neer really hear him say it. The grounds, which he gave Biddy, are his desires, his ain infatuation, or a? false love? . Pip has no existent land to wish, allow entirely love Estella since he barely knows her at all. All Pip knows is a immature miss, which was taught to interrupt work forces? s Black Marias. Estella is Miss Havisham? s mini me of her ego, a brokenhearted adult females who has no feelings of love, but merely hatred in her bosom. She taught Estella that work forces were bad because of her yesteryear, and Estella? s emotions and ideas we buried under Miss Havisham? s ideas. This was so early seen in the beginning when Estella proclaims that Pip is common. At this minute in clip, Pip felt bad and Estella knew it, but past that she says more contemptuous things in forepart of Miss Havisham for she knows it makes her proud maintaining her happy. This was atrocious because it kept Estella from of all time truly loving person throughout the whole novel. Statements like, ? Well? Can you interrupt his bosom? ? ( Dickens, 60 ) which are the beginning for individuality crises in this book amongst both Pip and Estella likewise. The actions which came from statements by Miss Havisham are what keeps Pip and Estella invariably traveling through out changeless individuality alterations, therefore doing it about near to impossible to love. Pip neer would be able to acquire a true appreciation of who she was because she, like him, would alter like the way of air current at any given clip. For a great continuance of the novel, Pip is infatuated with Estella. He thinks he is in love, but with no solid grounds as to why. As a reader, it can be perceived that Pip being a immature adult male, is traveling through alterations and is attracted physically to Estella nevertheless that can merely mensurate so much of love. This was shown when Biddy told Pip she liked him, but he opted for Estella. Pip experienced new feelings, which he neer had experienced, feelings that he doesn? T know about. Throughout the book we discover that his false love controls Pip. His infatuation for Estella inspires him to go an educated gentleman. We, like Pip have no thought how long he will experience like he does for Estella. We do cognize his infatuation is for the incorrect grounds. Pip truly didn? Ts have anybody or anything to compare his infatuation with, therefore it gave him no ground non hold 1. He neer had love earlier, non the love, go forthing him nil to compare to see if he is truly in love. Pip showed beyond a sensible uncertainty in his head, that he began with a deep infatuation for Estella. In the terminal of the novel, he learns that he does love Estella, and that his love will neer be common. Throughout the book Pip professes his love for Estella, but she ever says it can neer go on. He thinks that there is ever hope up until he finds out she is to be married to Drumle. In chapter 44 Pip makes a declaration to Miss Havisham in forepart of Estella, ? What I had to state to Estella, Miss Havisham, I will state before you, presently- in a few minutes. It will non surprise you, it will non displease you. I am every bit unhappy as you can of all time hold meant me to be? ( Dickens, 359 ) . This prepares Estella for what he is traveling to state, and assures that Miss Havisham has destroyed him as a adult male through Estella. Now that Miss Havisham is content, he turns to Estella, ? you know I love you, you know I have loved you long and in a heartfelt way? ( Dickens, 3 61 ) . Now Estella, along with, the reader know, he loves her officially, and he besides tells her, I should hold said this Oklahoman, but for my long error. It induced me to trust that Miss Havisham meant us for one another. While I thought you could non assist yourself, as it were, I refrained from stating it. But I must state it now. ( Dickens, 362 ) This is the preliminary to why he professes his love. He doesn? T want to see Estella get married Drummle for he knows he can non of all time achieve Estella? s love, but at the same clip he wants who of all time is traveling to get married her to handle her like a queen. He wants to outdo for her. His daring to be able to face a job, cognizing he will neer be apart of the solution shows how much so he does love her. But being Estella she replies to his statements by stating? ? When you say you love me, I know what you mean, as a signifier of words ; but nil more? ? ( Dickens, 362 ) . She makes it known that she has neer been in love, and is surely non in love with him. If Pip was infatuated with Estella he would hold begged and pleaded and be wholly against Estella get marrieding the Drummle, but he was mature alternatively and accepted what the deck had dealt him, trusting that she would be happy. Pip now comes to the realisation that he must travel on. Pip wants, finds, and trades with love. He knows that Estella is out of the image. He realizes from her stating I have no bosom, at this point in her life, she is incapable of love. He deals with this by wishing her the best and desiring the best for her. He will ever love her but he knows he can non hold her. In the beginning we think that he isn? T in love, for he doesn? t even cognize Estella, to the footings of what we think would be the foundation for any loving relationship. She treats him like dirt and attempts to do him experience like dirt 24 hours a twenty-four hours. The stating, ? the 1s you hate, are the 1s you truly love? , applies in this book. Deep beneath that difficult tegument, I think Estella has feelings for Pip-not needfully the feelings of love, but feelings. Through Pips tests and trials, he has learned all about love. Since Estella was his first infatuation, he had nil to compare his feelings to, but in the hereafter he will ever be able to compare. A good co njecture to how we can connote that he will love person would be if he thought of her as a queen. Pip learns and figures out love from everything he has been through. He is capable of loving and cognizing when love has begun and ended. But, like all good things ( like love and this paper ) they must come to an terminal until another good thing comes along ; another fantastic girl- a miss which loves Pip for Pip, as he does for her. Bibliography Work Citied WWWebster Dictionary? Love? Merriam-Webster, Incorporated 1999 ( 26 November 1999 ) Devils, Charles. Great Expectations. New York. Penguin Classic, 1996